| SAN DIEGO | 5-8 | BALTIMORE |
| PHILADELPHIA | 4-2 | S. FRANCISCO |
| BOSTON | 5-6 | TAMPA BAY |
| CLEVELAND | 0-2 | HOUSTON |
| TEXAS | 5-8 | SEATTLE |
| KANSAS CITY | 2-9 | TORONTO |
| COLORADO | 4-9 | LA DODGERS |
| OAKLAND | 3-2 | MILWAUKEE |
| NY YANKEES | 2-4 | ARIZONA |
| WASHINGTON | 8-11 | ATLANTA |
| CINCINNATI | 4-11 | PITTSBURGH |
| MIAMI | 1-2 | MINNESOTA |
| CGO. SOX | 2-5 | NY METS |
| ST LOUIS | 2-1 | CGO. CUBS |
| LA ANGELS | 6-1 | DETROIT |
| REAL ESTELI | 2-1 | SANTA TECLA |
| CRUZEIRO | 0-0 | RIVER PLATE |
| Aggregate 0-0- RIVER PLATE 4-2 on pen. | ||
| PALMEIRAS | 4-0 | GODOY CRUZ |
| Aggregate 6-2 | ||
| OLIMPIA | 1-1 | LDU QUITO |
| Aggregate 2-4 | ||
| SP. CRISTAL | 3-2 | ZULIA FC |
| Aggregate 3-3- ZULIA FC on away goals | ||
| FLUMINENSE | 3-1 | PENAROL |
| Aggregate 5-2 | ||
| KALJU | 0-2 | CELTIC |
| Aggregate 0-7 | ||
| VALLETTA | 1-1 | FERENCVAROS |
| Aggregate 2-4 | ||
| ZAGREB | 3-0 | FC IBERIA |
| Aggregate 5-0 | ||
| APOEL | 3-0 | SUTJESKA |
| Aggregate 4-0 | ||
| FC BASEL | 2-1 | PSV |
| Aggregate 4-4- FC BASEL on away goals | ||
| M. TEL-AVIV | 2-2 | CLUJ |
| Aggregate 2-3 | ||
| OLYMPIAKOS | 4-0 | PLZEN |
| Aggregate 4-0 | ||
| SUDUVA | 5-0 | TRE PENNE |
| Aggregate 10-0 | ||
| DUDELANGE | 1-1 | SHKENDIJA |
| Aggregate 3-2 | ||
| FERONIKELI | 0-2 | SLOVAN BRA. |
| Aggregate 1-4 | ||
| LINCOLN | 1-2 | ARARAT ARM. |
| Aggregate 1-4 | ||
| IRAQ | 1-0 | LEBANON |
| YEMEN | 0-1 | PALESTINE |
| WURZBURG | 0-3 | GROSSAPASCH |
| CZ IENA | 0-2 | BRAUNSCHWEIG |
| UERDINGEN | 2-2 | UNTERHACHING |
| KLAUTERN | 0-0 | INGOLSTADT |
| ROSTOCK | 2-1 | BAYERN II |
| FC KOLOS | 2-1 | FK MARIUPOL |
| CHERNIGOV | 1-2 | FK LVIV |
| WASHINGTON |
| Final |
| KYRGIOS def. MEDVEDEV |
| CABO SAN LUCAS |
| Final |
| SCHWARTZMAN def. FRITZ |
| KITZBUHEL |
| Final |
| THIEM def. RAMOS-VINOL |
| SAN JOSE |
| Final |
| ZHENG def. SABALENKA |
| WASHINGTON |
| Final |
| PEGULA def. GIORGI |
| KARLSRUHE |
| Final |
| TIG def. VAN UYTVANC |